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Honours students 2017-2018
Lauren Dolan, Stephen Jesmont and Samantha Kerrigan (all Applied Biomedical Science)
Worked on projects to compare gene expression levels of candidate genes in a range of tissues derived from SMA and control mice at different time points.
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Stephen was awarded the Ian Packer Memorial Prize for best Honours project.
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Naoimh Ledwith (Applied Biomedical Science), Akbar Shahid (Applied Biomedical Science) and Yoana Doncheva (Pharmacology)
Worked on projects to compare gene expression levels of candidate genes in range of tissues derived from SMA and control mice at different time points.
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![CYTSB intestine.png](https://static.wixstatic.com/media/54837e_2921d1aa99664766851f6f9c8b7e378e~mv2.png/v1/crop/x_0,y_34,w_307,h_213/fill/w_213,h_134,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/CYTSB%20intestine.png)
![CYTSB intestine.png](https://static.wixstatic.com/media/54837e_2921d1aa99664766851f6f9c8b7e378e~mv2.png/v1/crop/x_326,y_47,w_92,h_53/fill/w_77,h_44,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/CYTSB%20intestine.png)
28S
18S
![RNA extraction.jpg](https://static.wixstatic.com/media/54837e_959e1bcab47548edbc5ad937155f0a18~mv2.jpg/v1/crop/x_64,y_158,w_247,h_66/fill/w_203,h_22,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/RNA%20extraction.jpg)
Figure 1. Assessment of RNA quality by gel electrophoresis.
![CYTSB brain lung.jpg](https://static.wixstatic.com/media/54837e_a2a7da4ef295471ba4d5f82cbf41947f~mv2.jpg/v1/crop/x_58,y_126,w_535,h_367/fill/w_211,h_134,al_c,q_80,usm_0.66_1.00_0.01,enc_auto/CYTSB%20brain%20lung.jpg)
Figure 2. Quantification of total CYTSB gene expression in intestinal tissue from SMA-derived and control mice at a range of ages.
Figure 3. Quantification of total CYTSB gene expression in brain and lung tissue from SMA-derived and control mice at early (P0) and late (P8) symptomatic time points.
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